Compile Data Set for Download or QSAR
maximum 50k data
Found 646 of ic50 for Alpha glucosidase
having polymerids = 50001107,50001875,9427 and
complexids = 50015970
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50539421(CHEMBL4634355)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate incubated for 20 mins by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024139(1-Hydroxymethyl-5-phenethylamino-cyclohexane-1,2,3...)
Affinity DataIC50:  2.30nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024120(1-Hydroxymethyl-5-[(thiophen-2-ylmethyl)-amino]-cy...)
Affinity DataIC50:  3.30nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50226273(CHEMBL3349431)
Affinity DataIC50:  4.60nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50405397(CHEMBL2051983)
Affinity DataIC50:  4.90nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024119(5-(2-Hydroxy-cyclohexylamino)-1-hydroxymethyl-cycl...)
Affinity DataIC50:  5.20nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024137(1-Hydroxymethyl-5-(2-hydroxy-2-phenyl-ethylamino)-...)
Affinity DataIC50:  5.80nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50024137(1-Hydroxymethyl-5-(2-hydroxy-2-phenyl-ethylamino)-...)
Affinity DataIC50:  5.80nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50024119(5-(2-Hydroxy-cyclohexylamino)-1-hydroxymethyl-cycl...)
Affinity DataIC50:  6.10nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024136(5-(3,5-Di-tert-butyl-4-hydroxy-benzylamino)-1-hydr...)
Affinity DataIC50:  6.80nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405395(CHEMBL2051761)
Affinity DataIC50:  7.5nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024114(5-(Cyclohexylmethyl-amino)-1-hydroxymethyl-cyclohe...)
Affinity DataIC50:  9.30nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405397(CHEMBL2051983)
Affinity DataIC50:  10nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283602(6a-Hydroxymethyl-2-phenylamino-4,5,6,6a-tetrahydro...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity was determined against baker's yeast Alpha-GlucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024118(5-(3,7-Dimethyl-octa-2,6-dienylamino)-1-hydroxymet...)
Affinity DataIC50:  11nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50024124(1-Hydroxymethyl-5-(2-hydroxy-1-phenyl-ethylamino)-...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024124(1-Hydroxymethyl-5-(2-hydroxy-1-phenyl-ethylamino)-...)
Affinity DataIC50:  13nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024133(1-Hydroxymethyl-5-(3-phenyl-allylamino)-cyclohexan...)
Affinity DataIC50:  14nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024128(5-(4-Bromo-benzylamino)-1-hydroxymethyl-cyclohexan...)
Affinity DataIC50:  15nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024126(1-Hydroxymethyl-5-[(pyridin-3-ylmethyl)-amino]-cyc...)
Affinity DataIC50:  15nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024117(5-Cyclohexylamino-1-hydroxymethyl-cyclohexane-1,2,...)
Affinity DataIC50:  15nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50226273(CHEMBL3349431)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50405395(CHEMBL2051761)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405389(CHEMBL2051982)
Affinity DataIC50:  35nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405396(CHEMBL2051762)
Affinity DataIC50:  36nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50259956(2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity measured against alpha-glucosidase of rice by colorimetric assay using the D-glucose oxidase-peroxidase methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against human alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50024136(5-(3,5-Di-tert-butyl-4-hydroxy-benzylamino)-1-hydr...)
Affinity DataIC50:  43nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024129(5-Amino-1-hydroxymethyl-cyclohexane-1,2,3,4-tetrao...)
Affinity DataIC50:  49nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50:  60nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50405396(CHEMBL2051762)
Affinity DataIC50:  68nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  70nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50405389(CHEMBL2051982)
Affinity DataIC50:  70nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50405393(CHEMBL2051981)
Affinity DataIC50:  72nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50611854(CHEMBL5271914)
Affinity DataIC50:  77nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate preincubated for 15 mins followed by substrate addition by microplate reader...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50405393(CHEMBL2051981)
Affinity DataIC50:  80nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50613821(CHEMBL4854113)
Affinity DataIC50:  82nMAssay Description:Inhibition of alpha glucosidase (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50611832(CHEMBL4856778)
Affinity DataIC50:  85nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate preincubated for 15 mins followed by substrate addition by microplate reader...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50405387(CHEMBL2051759)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human lysosomal alpha glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50259956(2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)
Affinity DataIC50:  100nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50024139(1-Hydroxymethyl-5-phenethylamino-cyclohexane-1,2,3...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against porcine maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50613819(CHEMBL3944972)
Affinity DataIC50:  120nMAssay Description:Inhibition of alpha glucosidase (unknown origin) using p-nitrophenyl glucopyranoside as substrate pre incubated for 10 mins followed by substrate add...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)
Affinity DataIC50:  120nMAssay Description:Inhibition of Glycosidases (maltase) in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM628474(US20230339856, Compound (IId))
Affinity DataIC50:  150nMAssay Description:The rhGAA enzyme sold under the name Myozyme® used comes from residues of perfusions of the recombinant enzyme used for treating, by enzyme therapy, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50180584(CHEMBL3814496)
Affinity DataIC50:  150nMAssay Description:Inhibition of human small intestine microsomal maltase using maltose as substrate incubated for 30 mins by glucose-oxidase methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024127(5-(2-Hydroxy-cyclohexylamino)-1-hydroxymethyl-cycl...)
Affinity DataIC50:  160nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50:  172nMAssay Description:Inhibition of alpha glucosidase (unknown origin) using p-nitrophenyl glucopyranoside as substrate by UV Vis- spectrophotometer analysisMore data for this Ligand-Target Pair
TargetSucrase-isomaltase, intestinal(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50024122(6-(2-Hydroxy-1-hydroxymethyl-ethylamino)-4-hydroxy...)
Affinity DataIC50:  180nMAssay Description:Alpha-D-glucosidase inhibitory activity and enzyme inhibition in vitro against porcine sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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